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NADPH oxidase inhibition prevents beta cell dysfunction induced by prolonged elevation of oleate in rodents.

  • Author(s): Desai, Tejal
  • Koulajian, K
  • Liu, GC
  • Ivovic, A
  • Patterson, JN
  • Tang, C
  • El-Benna, J
  • Joseph, JW
  • Scholey, JW
  • Giacca, A
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3622749?pdf=render
No data is associated with this publication.
Abstract

The activation of NADPH oxidase has been implicated in NEFA-induced beta cell dysfunction. However, the causal role of this activation in vivo remains unclear. Here, using rodents, we investigated whether pharmacological or genetic inhibition of NADPH oxid

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