NADPH oxidase inhibition prevents beta cell dysfunction induced by prolonged elevation of oleate in rodents.
Published Web Locationhttp://europepmc.org/articles/PMC3622749?pdf=render
The activation of NADPH oxidase has been implicated in NEFA-induced beta cell dysfunction. However, the causal role of this activation in vivo remains unclear. Here, using rodents, we investigated whether pharmacological or genetic inhibition of NADPH oxid