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Compartmentalization of GABA synthesis by GAD67 differs between pancreatic beta cells and neurons

  • Author(s): Baekkeskov, Steinunn;
  • Kanaani, J;
  • Cianciaruso, C;
  • Phelps, EA;
  • Pasquier, M;
  • Brioudes, E;
  • Billestrup, N
  • et al.

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© 2015 PLOS ONE.The inhibitory neurotransmitter GABA is synthesized by the enzyme glutamic acid decarboxylase (GAD) in neurons and in pancreatic β-cells in islets of Langerhans where it functions as a paracrine and autocrine signaling molecule regulating t

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