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Whole-genome analysis informs breast cancer response to aromatase inhibition

  • Author(s): Esserman, Laura;
  • Ellis, MJ;
  • Ding, L;
  • Shen, D;
  • Luo, J;
  • Suman, VJ;
  • Wallis, JW;
  • Van, BA;
  • Hoog, J;
  • Goiffon, RJ;
  • Goldstein, TC
  • et al.

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To correlate the variable clinical features of oestrogen-receptor-positive breast cancer with somatic alterations, we studied pretreatment tumour biopsies accrued from patients in two studies of neoadjuvant aromatase inhibitor therapy by massively parallel

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