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Open Access Publications from the University of California

Imaging breast cancer chemotherapy response with light. Commentary on Soliman et al., p. 2605.

  • Author(s): Tromberg, Bruce J
  • Cerussi, Albert E
  • et al.

Diffuse optical spectroscopy (DOS), which is used to image tumor metabolic response to neoadjuvant chemotherapy (NAC), shows large changes in tumor functional parameters with significant reductions in oxy- and deoxyhemoglobin for responders versus nonresponders. Although investigational, DOS may provide a cost-effective, risk-free method for optimizing NAC drug and dosing strategies for individual patients.

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