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Newly exerted T cell pressures on mutated epitopes following transmission help maintain consensus HIV-1 sequences

  • Author(s): Hecht, Frederick
  • Pilcher, Christopher
  • Eriksson, EM
  • Liegler, T
  • Keh, CE
  • Karlsson, AC
  • Holditch, SJ
  • Pilcher, CD
  • Loeb, L
  • Nixon, DF
  • Hecht, FM
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4412704?pdf=render
No data is associated with this publication.
Abstract

© 2015 Eriksson et al.CD8+ T cells are important for HIV-1 virus control, but are also a major contributing factor that drives HIV-1 virus sequence evolution. Although HIV-1 cytotoxic T cell (CTL) escape mutations are a common aspect during HIV-

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