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AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine

  • Author(s): Muschen, Markus
  • Tsai, CT
  • Yang, PM
  • Chern, TR
  • Chuang, SH
  • Lin, JH
  • Klemm, L
  • Müschen, M
  • Chen, CC
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3960202?pdf=render
No data is associated with this publication.
Abstract

Activation-induced cytidine deaminase (AID) was originally identified as an inducer of somatic hypermutation (SHM) and class switch recombination (CSR) in immunoglobulin genes. However, AID can also cause mutations in host genes and contribute to cancer pr

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