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Open Access Publications from the University of California

AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine

  • Author(s): Muschen, Markus
  • Tsai, CT
  • Yang, PM
  • Chern, TR
  • Chuang, SH
  • Lin, JH
  • Klemm, L
  • Müschen, M
  • Chen, CC
  • et al.

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Activation-induced cytidine deaminase (AID) was originally identified as an inducer of somatic hypermutation (SHM) and class switch recombination (CSR) in immunoglobulin genes. However, AID can also cause mutations in host genes and contribute to cancer pr

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