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Hyperplasia of interstitial cells of cajal in sprouty homolog 4 deficient mice

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http://europepmc.org/articles/PMC4414615?pdf=render
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Abstract

© 2015 Thys et al.Gastrointestinal stromal tumors, which are thought to derive from interstitial cells of Cajal or their precursors, often harbor an oncogenic mutation of the KIT receptor tyrosine kinase. Sprouty homolog 4, a known negative regulator of ER

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