Zuffa, Simone; Schmid, Robin; Bauermeister, Anelize; P. Gomes, Paulo Wender; Caraballo-Rodriguez, Andres M; El Abiead, Yasin; Aron, Allegra T; Gentry, Emily C; Zemlin, Jasmine; Meehan, Michael J; Avalon, Nicole E; Cichewicz, Robert H; Buzun, Ekaterina; Terrazas, Marvic Carrillo; Hsu, Chia-Yun; Oles, Renee; Ayala, Adriana Vasquez; Zhao, Jiaqi; Chu, Hiutung; Kuijpers, Mirte CM; Jackrel, Sara L; Tugizimana, Fidele; Nephali, Lerato Pertunia; Dubery, Ian A; Madala, Ntakadzeni Edwin; Moreira, Eduarda Antunes; Costa-Lotufo, Leticia Veras; Lopes, Norberto Peporine; Rezende-Teixeira, Paula; Jimenez, Paula C; Rimal, Bipin; Patterson, Andrew D; Traxler, Matthew F; Pessotti, Rita de Cassia; Alvarado-Villalobos, Daniel; Tamayo-Castillo, Giselle; Chaverri, Priscila; Escudero-Leyva, Efrain; Quiros-Guerrero, Luis-Manuel; Bory, Alexandre Jean; Joubert, Juliette; Rutz, Adriano; Wolfender, Jean-Luc; Allard, Pierre-Marie; Sichert, Andreas; Pontrelli, Sammy; Pullman, Benjamin S; Bandeira, Nuno; Gerwick, William H; Gindro, Katia; Massana-Codina, Josep; Wagner, Berenike C; Forchhammer, Karl; Petras, Daniel; Aiosa, Nicole; Garg, Neha; Liebeke, Manuel; Bourceau, Patric; Kang, Kyo Bin; Gadhavi, Henna; de Carvalho, Luiz Pedro Sorio; Silva dos Santos, Mariana; Pérez-Lorente, Alicia Isabel; Molina-Santiago, Carlos; Romero, Diego; Franke, Raimo; Brönstrup, Mark; Vera Ponce de León, Arturo; Pope, Phillip Byron; La Rosa, Sabina Leanti; La Barbera, Giorgia; Roager, Henrik M; Laursen, Martin Frederik; Hammerle, Fabian; Siewert, Bianka; Peintner, Ursula; Licona-Cassani, Cuauhtemoc; Rodriguez-Orduña, Lorena; Rampler, Evelyn; Hildebrand, Felina; Koellensperger, Gunda; Schoeny, Harald; Hohenwallner, Katharina; Panzenboeck, Lisa; Gregor, Rachel

doi:10.1038/s41564-023-01575-9

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microbeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics data

2024

Zuffa, Simone;
Schmid, Robin;
Bauermeister, Anelize;
P. Gomes, Paulo Wender;
Caraballo-Rodriguez, Andres M;
El Abiead, Yasin;
Aron, Allegra T;
Gentry, Emily C;
Zemlin, Jasmine;
Meehan, Michael J;
Avalon, Nicole E;
Cichewicz, Robert H;
Buzun, Ekaterina;
Terrazas, Marvic Carrillo;
Hsu, Chia-Yun;
Oles, Renee;
Ayala, Adriana Vasquez;
Zhao, Jiaqi;
Chu, Hiutung;
Kuijpers, Mirte CM;
Jackrel, Sara L;
Tugizimana, Fidele;
Nephali, Lerato Pertunia;
Dubery, Ian A;
Madala, Ntakadzeni Edwin;
Moreira, Eduarda Antunes;
Costa-Lotufo, Leticia Veras;
Lopes, Norberto Peporine;
Rezende-Teixeira, Paula;
Jimenez, Paula C;
Rimal, Bipin;
Patterson, Andrew D;
Traxler, Matthew F;
Pessotti, Rita de Cassia;
Alvarado-Villalobos, Daniel;
Tamayo-Castillo, Giselle;
Chaverri, Priscila;
Escudero-Leyva, Efrain;
Quiros-Guerrero, Luis-Manuel;
Bory, Alexandre Jean;
Joubert, Juliette;
Rutz, Adriano;
Wolfender, Jean-Luc;
Allard, Pierre-Marie;
Sichert, Andreas;
Pontrelli, Sammy;
Pullman, Benjamin S;
Bandeira, Nuno;
Gerwick, William H;
Gindro, Katia;
Massana-Codina, Josep;
Wagner, Berenike C;
Forchhammer, Karl;
Petras, Daniel;
Aiosa, Nicole;
Garg, Neha;
Liebeke, Manuel;
Bourceau, Patric;
Kang, Kyo Bin;
Gadhavi, Henna;
de Carvalho, Luiz Pedro Sorio;
Silva dos Santos, Mariana;
Pérez-Lorente, Alicia Isabel;
Molina-Santiago, Carlos;
Romero, Diego;
Franke, Raimo;
Brönstrup, Mark;
Vera Ponce de León, Arturo;
Pope, Phillip Byron;
La Rosa, Sabina Leanti;
La Barbera, Giorgia;
Roager, Henrik M;
Laursen, Martin Frederik;
Hammerle, Fabian;
Siewert, Bianka;
Peintner, Ursula;
Licona-Cassani, Cuauhtemoc;
Rodriguez-Orduña, Lorena;
Rampler, Evelyn;
Hildebrand, Felina;
Koellensperger, Gunda;
Schoeny, Harald;
Hohenwallner, Katharina;
Panzenboeck, Lisa;
Gregor, Rachel;
O’Neill, Ellis Charles;
Roxborough, Eve Tallulah;
Odoi, Jane;
Bale, Nicole J;
Ding, Su;
Sinninghe Damsté, Jaap S;
Guan, Xue Li;
Cui, Jerry J;
Ju, Kou-San;
Silva, Denise Brentan;
Silva, Fernanda Motta Ribeiro;
da Silva, Gilvan Ferreira;
Koolen, Hector HF;
Grundmann, Carlismari;
Clement, Jason A;
Mohimani, Hosein;
Broders, Kirk;
McPhail, Kerry L;
Ober-Singleton, Sidnee E;
Rath, Christopher M;
McDonald, Daniel;
Knight, Rob;
Wang, Mingxun;
Dorrestein, Pieter C

et al.

Published Web Location

https://doi.org/10.1038/s41564-023-01575-9

Creative Commons 'BY' version 4.0 license

Abstract

AbstractmicrobeMASST, a taxonomically informed mass spectrometry (MS) search tool, tackles limited microbial metabolite annotation in untargeted metabolomics experiments. Leveraging a curated database of >60,000 microbial monocultures, users can search known and unknown MS/MS spectra and link them to their respective microbial producers via MS/MS fragmentation patterns. Identification of microbe-derived metabolites and relative producers without a priori knowledge will vastly enhance the understanding of microorganisms’ role in ecology and human health.

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microbeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics data

Published Web Location