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A Proteomic Map to Navigate Subcellular Reorganization in Fatty Liver Disease
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https://doi.org/10.1016/j.devcel.2018.10.006Abstract
In a tour de force in this issue of Developmental Cell, Krahmer et al. leverage proteomic platforms to reveal subcellular proteome dynamics during development of nonalcoholic fatty liver disease. Their findings uncover a remarkable degree of subcellular reorganization, alterations in protein localization, and remodeling of organelle contact sites.
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