Cis-acting pathways selectively enforce the non-immunogenicity of shed placental antigen for maternal CD8 T cells.
- Author(s): Erlebacher, Adrian
- Tay, C-S
- Tagliani, E
- Collins, MK
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3877187?pdf=render
Maternal immune tolerance towards the fetus and placenta is thought to be established in part by pathways that attenuate T cell priming to antigens released from the placenta into maternal blood. These pathways remain largely undefined and their existence,