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Delivery of an active lysosomal enzyme using GNeosomes.
- Author(s): Hamill, Kristina M
- Wexselblatt, Ezequiel
- Tong, Wenyong
- Esko, Jeffrey D
- Tor, Yitzhak
- et al.
Published Web Locationhttps://doi.org/10.1039/c6tb01387b
Two methods for assembling guanidinoneomycin-decorated liposomes are presented and their ability to deliver an active enzyme to the lysosomes and restore enzyme function in diseased cells is compared.