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Delivery of an active lysosomal enzyme using GNeosomes.

  • Author(s): Hamill, Kristina M
  • Wexselblatt, Ezequiel
  • Tong, Wenyong
  • Esko, Jeffrey D
  • Tor, Yitzhak
  • et al.
Abstract

Two methods for assembling guanidinoneomycin-decorated liposomes are presented and their ability to deliver an active enzyme to the lysosomes and restore enzyme function in diseased cells is compared.

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