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Open Access Publications from the University of California

Low-intensity late gadolinium enhancement predominates in hypertrophic cardiomyopathy.

  • Author(s): Naeger, David M
  • Higgins, Charles
  • De Marco, Teresa
  • Muzzarelli, Stefano
  • Ordovas, Karen G
  • et al.

Assess the extent of low- versus high-intensity late gadolinium enhancement (LGE) in hypertrophic cardiomyopathy (HCM).Low- versus high-intensity LGE indexed volumes in 19 HCM patients were compared to 23 myocardial infarction (MI) patients.Total, low-, and high-intensity LGE volumes in HCM vs. MI were 7.6ml/m(2), 4.7, and 2.4 vs. 11.2, 2.5, and 7.1, respectively. Total LGE volume did not differ (P=.13), though low- and high-intensity did (P=.05, .004). 67% versus 26% of all LGE was low-intensity in HCM versus MI (P<.001).LGE in HCM is predominantly low-intensity, so a low threshold may be the most appropriate.

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