A20 restricts wnt signaling in intestinal epithelial cells and suppresses colon carcinogenesis.
- Author(s): Ma, Averil
- Shao, L
- Oshima, S
- Duong, B
- Advincula, R
- Barrera, J
- Malynn, BA
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3645994?pdf=render
Colon carcinogenesis consists of a multistep process during which a series of genetic and epigenetic adaptations occur that lead to malignant transformation. Here, we have studied the role of A20 (also known as TNFAIP3), a ubiquitin-editing enzyme that res
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