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A20 restricts wnt signaling in intestinal epithelial cells and suppresses colon carcinogenesis.

  • Author(s): Ma, Averil
  • Shao, L
  • Oshima, S
  • Duong, B
  • Advincula, R
  • Barrera, J
  • Malynn, BA
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3645994?pdf=render
No data is associated with this publication.
Abstract

Colon carcinogenesis consists of a multistep process during which a series of genetic and epigenetic adaptations occur that lead to malignant transformation. Here, we have studied the role of A20 (also known as TNFAIP3), a ubiquitin-editing enzyme that res

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