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Combining anti-ERBB3 antibodies specific for domain I and domain III enhances the anti-tumor activity over the individual monoclonal antibodies

  • Author(s): Marks, James
  • D'Souza, JW
  • Reddy, S
  • Goldsmith, LE
  • Shchaveleva, I
  • Marks, JD
  • Litwin, S
  • Robinson, MK
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4227695?pdf=render
No data is associated with this publication.
Abstract

© 2014 D'Souza et al.Background: Inappropriate signaling through the epidermal growth factor receptor family (EGFR1/ERBB1, ERBB2/HER2, ERBB3/HER3, and ERBB4/HER4) of receptor tyrosine kinases leads to unregulated activation of multiple downstream signaling

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