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MOG transmembrane and cytoplasmic domains contain highly stimulatory T-cell epitopes in MS.
- Author(s): Zamvil, Scott;
- Cree, Bruce;
- Varrin-Doyer, M;
- Shetty, A;
- Spencer, CM;
- Schulze-Topphoff, U;
- Weber, MS;
- Bernard, CCA;
- Forsthuber, T;
- Cree, BAC;
- Slavin, AJ;
- Zamvil, SS
- et al.
Published Web Location
http://europepmc.org/articles/PMC4202926?pdf=renderNo data is associated with this publication.
Abstract
OBJECTIVE: Recently, we reported that the 218 amino acid murine full-length myelin oligodendrocyte glycoprotein (MOG) contains novel T-cell epitopes p119-132, p181-195, and p186-200, located within its transmembrane and cytoplasmic domains, and that p119-1
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