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Crystal structure of a eukaryotic phosphate transporter
- Pedersen, Bjørn P;
- Kumar, Hemant;
- Waight, Andrew B;
- Risenmay, Aaron J;
- Roe-Zurz, Zygy;
- Chau, Bryant H;
- Schlessinger, Avner;
- Bonomi, Massimiliano;
- Harries, William;
- Sali, Andrej;
- Johri, Atul K;
- Stroud, Robert M
Published Web Location
https://doi.org/10.1038/nature12042Abstract
The X-ray crystal structure of a high-affinity phosphate importer in an inward-facing, occluded state in the presence of phosphate is reported; this is the first structure of a membrane protein involved in inorganic phosphate uptake and the first crystal structure of a eukaryotic MFS transporter.
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