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Golgi fragmentation precedes neuromuscular denervation and is associated with endosome abnormalities in SOD1-ALS mouse motor neurons.

  • Author(s): Oakes, Scott;
  • van, V;
  • Kuijpers, M;
  • Haasdijk, ED;
  • Teuling, E;
  • Oakes, SA;
  • Hoogenraad, CC;
  • Jaarsma, D
  • et al.

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Fragmentation of stacked cisterns of the Golgi apparatus into dispersed smaller elements is a feature associated with degeneration of neurons in amyotrophic lateral sclerosis (ALS) and some other neurodegenerative disorders. However, the role of Golgi frag

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