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Physical Activity is Associated with Better Neurocognitive and Everyday Functioning Among Older Adults with HIV Disease

  • Author(s): Fazeli, PL
  • Marquine, MJ
  • Dufour, C
  • Henry, BL
  • Montoya, J
  • Gouaux, B
  • Moore, RC
  • Letendre, SL
  • Woods, SP
  • Grant, I
  • Jeste, DV
  • Moore, DJ
  • et al.

Published Web Location

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527965/
No data is associated with this publication.
Abstract

© 2015, Springer Science+Business Media New York. We examined the association between physical activity (PA), neurocognitive impairment (NCI), and instrumental activities of daily living (IADLs) among older HIV+ persons. One hundred older HIV+ adults completed the International Physical Activity Questionnaire, a neurocognitive battery, and IADL scale. Higher levels of moderate PA were associated with lower odds of NCI (p = 0.01), even when covariates were modeled. The association between moderate PA and NCI was driven by executive function (p = 0.04). Higher levels of moderate PA were also associated with lower odds of IADL Dependence (p = 0.03), although this fell to a trend (p = 0.08) when including covariates. Follow-up analysis showed those with both NCI and IADL Dependence had lower moderate PA than those with neither (p = 0.03). While these cross-sectional findings suggest PA is associated with better neurocognitive and everyday functioning in older HIV+ adults, longitudinal studies utilizing objective PA methods are needed to evaluate directionality and mechanisms.

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