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SNP imputation bias reduces effect size determination

  • Author(s): Gourraud, Pierre-Antoine
  • Baranzini, Sergio
  • Khankhanian, P
  • Din, L
  • Caillier, SJ
  • Gourraud, PA
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4321633?pdf=render
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Abstract

© 2015 Khankhanian, Din, Caillier, Gourraud and Baranzini.Imputation is a commonly used technique that exploits linkage disequilibrium to infer missing genotypes in genetic datasets, using a well-characterized reference population. While there is agreement

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