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Exposing Hidden Alternative Backbone Conformations in X-ray Crystallography Using qFit

  • Author(s): Fraser, James
  • Keedy, DA
  • Fraser, JS
  • van, H
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4624436?pdf=render
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Abstract

© 2015 Keedy et al.Proteins must move between different conformations of their native ensemble to perform their functions. Crystal structures obtained from high-resolution X-ray diffraction data reflect this heterogeneity as a spatial and temporal conforma

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