Exposing Hidden Alternative Backbone Conformations in X-ray Crystallography Using qFit
- Author(s): Fraser, James
- Keedy, DA
- Fraser, JS
- van, H
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC4624436?pdf=render
© 2015 Keedy et al.Proteins must move between different conformations of their native ensemble to perform their functions. Crystal structures obtained from high-resolution X-ray diffraction data reflect this heterogeneity as a spatial and temporal conforma
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