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Open Access Publications from the University of California

Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice

  • Author(s): Baranzini, Sergio
  • Han, MH
  • Lundgren, DH
  • Jaiswa, S
  • Chao, M
  • Graham, KL
  • Garris, CS
  • Axtell, RC
  • Ho, PP
  • Lock, CB
  • Woodard, JI
  • et al.

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Comparison of transcriptomic and proteomic data from pathologically similar multiple sclerosis (MS) lesions reveals down-regulation of CD47 at the messenger RNA level and low abundance at the protein level. Immunohistochemical studies demonstrate that CD47

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