Skip to main content
Open Access Publications from the University of California

GO-Elite: A flexible solution for pathway and ontology over-representation

  • Author(s): Zambon, AC
  • Gaj, S
  • Ho, I
  • Hanspers, K
  • Vranizan, K
  • Evelo, CT
  • Conklin, BR
  • Pico, AR
  • Salomonis, N
  • et al.

Published Web Location
No data is associated with this publication.

Summary: We introduce GO-Elite, a flexible and powerful pathway analysis tool for a wide array of species, identifiers (IDs), pathways, ontologies and gene sets. In addition to the Gene Ontology (GO), GO-Elite allows the user to perform over-representation analysis on any structured ontology annotations, pathway database or biological IDs (e.g. gene, protein or metabolite). GO-Elite exploits the structured nature of biological ontologies to report a minimal set of non-overlapping terms. The results can be visualized on WikiPathways or as networks. Built-in support is provided for over 60 species and 50 ID systems, covering gene, disease and phenotype ontologies, multiple pathway databases, biomarkers, and transcription factor and microRNA targets. GO-Elite is available as a web interface, GenMAPP-CS plugin and as a cross-platform application. © The Author(s) 2012. Published by Oxford University Press.

Many UC-authored scholarly publications are freely available on this site because of the UC Academic Senate's Open Access Policy. Let us know how this access is important for you.

Main Content

This item is under embargo until December 31, 2999.