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Open Access Publications from the University of California

A compact, in vivo screen of all 6-mers reveals drivers of tissue-specific expression and guides synthetic regulatory element design

  • Author(s): Ahituv, Nadav
  • Pollard, Katherine
  • Smith, RP
  • Riesenfeld, SJ
  • Holloway, AK
  • Li, Q
  • Murphy, KK
  • Feliciano, NM
  • Orecchia, L
  • Oksenberg, N
  • Pollard, KS
  • et al.

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Background: Large-scale annotation efforts have improved our ability to coarsely predict regulatory elements throughout vertebrate genomes. However, it is unclear how complex spatiotemporal patterns of gene expression driven by these elements emerge from t

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