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A NAC Gene regulating senescence improves grain protein, zinc, and iron content in wheat.

  • Author(s): Uauy, Cristobal
  • Distelfeld, Assaf
  • Fahima, Tzion
  • Blechl, Ann
  • Dubcovsky, Jorge
  • et al.

Published Web Location

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737439/
No data is associated with this publication.
Abstract

Enhancing the nutritional value of food crops is a means of improving human nutrition and health. We report here the positional cloning of Gpc-B1, a wheat quantitative trait locus associated with increased grain protein, zinc, and iron content. The ancestral wild wheat allele encodes a NAC transcription factor (NAM-B1) that accelerates senescence and increases nutrient remobilization from leaves to developing grains, whereas modern wheat varieties carry a nonfunctional NAM-B1 allele. Reduction in RNA levels of the multiple NAM homologs by RNA interference delayed senescence by more than 3 weeks and reduced wheat grain protein, zinc, and iron content by more than 30%.

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