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Open Access Publications from the University of California

Spotlight on CRISPR in Strongyloides Parasitic Nematodes.

  • Author(s): Ward, Jordan D
  • et al.

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Parasitic nematodes are biomedically and economically important, but many are genetically intractable which limits our understanding of their molecular and cellular biology. Gang et al. report CRISPR/Cas9 genome editing in parasites of the genus Strongyloides, generating both knock-outs and knock-ins, and demonstrated heritability of the modifications, a crucial advance in the field.

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