A structure-based model for predicting serum albumin binding
- Author(s): Jacobson, Matthew
- Lexa, KW
- Dolghih, E
- Jacobson, MP
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3972100?pdf=render
One of the many factors involved in determining the distribution and metabolism of a compound is the strength of its binding to human serum albumin. While experimental and QSAR approaches for determining binding to albumin exist, various factors limit thei