Biochemical and immunological mechanisms by which sickle cell trait protects against malaria
- Author(s): Rosenthal, Philip
- Greenhouse, Bryan
- Gong, L
- Parikh, S
- Rosenthal, PJ
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3847285?pdf=render
Sickle cell trait (HbAS) is the best-characterized genetic polymorphism known to protect against falciparum malaria. Although the protective effect of HbAS against malaria is well known, the mechanism(s) of protection remain unclear. A number of biochemica
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