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YM155 potently kills acute lymphoblastic leukemia cells through activation of the DNA damage pathway

  • Author(s): Muschen, Markus
  • Chang, BH
  • Johnson, K
  • LaTocha, D
  • Rowley, JSJ
  • Bryant, J
  • Burke, R
  • Smith, RL
  • Loriaux, M
  • Müschen, M
  • Mullighan, C
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4408565?pdf=render
No data is associated with this publication.
Abstract

© 2015 Chang et al.; licensee BioMed Central.Background: Novel-targeted therapies are in rapid development for the treatment of acute lymphoblastic leukemia (ALL) to overcome resistance and decrease toxicity. Survivin, a member of the inhibitor of apoptosi

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