Further intracellular proteins and signaling pathways regulated by angiotensin-(1-7) in human endothelial cells.
- Author(s): Meinert, Christian;
- Kohse, Franziska;
- Böhme, Ilka;
- Gembardt, Florian;
- Tetzner, Anja;
- Wieland, Thomas;
- Greenberg, Barry;
- Walther, Thomas
- et al.
Published Web Locationhttps://doi.org/10.1016/j.dib.2016.12.004
In 2016, Meinert et al. (doi: 10.1016/j.jprot.2015.09.020) published the first 25 proteins in a protein array regulated in Human Umbilical Vein Endothelial Cells (HUVEC) by the heptapeptide angiotensin (Ang)-(1-7) and the first 10 intracellular signaling cascades at different time points. This supporting data article shows further proteins and pathways stimulated by Ang-(1-7) in human endothelial cells at time points of 1 h, 3 h, 6 h, and 9 h. HUVECs were stimulated with Ang-(1-7), and regulated proteins were identified via antibody microarray. Bioinformatics software IPA was used for association of regulated proteins to metabolic pathways.