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The Landscape of Human Cancer Proteins Targeted by SARS-CoV-2
- Tutuncuoglu, Beril;
- Cakir, Merve;
- Batra, Jyoti;
- Bouhaddou, Mehdi;
- Eckhardt, Manon;
- Gordon, David E;
- Krogan, Nevan J
Published Web Location
https://doi.org/10.1158/2159-8290.cd-20-0559Abstract
The mapping of SARS-CoV-2 human protein-protein interactions by Gordon and colleagues revealed druggable targets that are hijacked by the virus. Here, we highlight several oncogenic pathways identified at the host-virus interface of SARS-CoV-2 to enable cancer biologists to apply their knowledge for rapid drug repurposing to treat COVID-19, and help inform the response to potential long-term complications of the disease.
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