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The Landscape of Human Cancer Proteins Targeted by SARS-CoV-2.

  • Author(s): Tutuncuoglu, Beril;
  • Cakir, Merve;
  • Batra, Jyoti;
  • Bouhaddou, Mehdi;
  • Eckhardt, Manon;
  • Gordon, David E;
  • Krogan, Nevan J
  • et al.
Abstract

The mapping of SARS-CoV-2 human protein-protein interactions by Gordon and colleagues revealed druggable targets that are hijacked by the virus. Here, we highlight several oncogenic pathways identified at the host-virus interface of SARS-CoV-2 to enable cancer biologists to apply their knowledge for rapid drug repurposing to treat COVID-19, and help inform the response to potential long-term complications of the disease.

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