The Landscape of Human Cancer Proteins Targeted by SARS-CoV-2.
- Author(s): Tutuncuoglu, Beril
- Cakir, Merve
- Batra, Jyoti
- Bouhaddou, Mehdi
- Eckhardt, Manon
- Gordon, David E
- Krogan, Nevan J
- et al.
Published Web Locationhttps://doi.org/10.1158/2159-8290.cd-20-0559
The mapping of SARS-CoV-2 human protein-protein interactions by Gordon and colleagues revealed druggable targets that are hijacked by the virus. Here, we highlight several oncogenic pathways identified at the host-virus interface of SARS-CoV-2 to enable cancer biologists to apply their knowledge for rapid drug repurposing to treat COVID-19, and help inform the response to potential long-term complications of the disease.