Orthodontic and surgical management of cleidocranial dysplasia
- Author(s): Oberoi, Snehlata
- Vargervik, Karin
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3822065?pdf=render
Cleidocranial dysplasia (CCD), an autosomal dominant disorder with a prevalence of 1 in 1,000,000 individuals, is mainly caused by mutations in Runx2, a gene required for osteoblastic differentiation. It is generally characterized by hypoplastic clavicles,