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A neuropathologic diagnosis of Alzheimer's disease in an older adult with HIV-associated neurocognitive disorder.

  • Author(s): Hellmuth, Joanna
  • Milanini, Benedetta
  • Masliah, Eliezer
  • Tartaglia, Maria Carmela
  • Dunlop, Miranda B
  • Moore, David J
  • Javandel, Shireen
  • DeVaughn, Saskia
  • Valcour, Victor
  • et al.

Published Web Location

https://www.tandfonline.com/doi/full/10.1080/13554794.2018.1530362
No data is associated with this publication.
Abstract

We discuss the challenges associated with diagnosing neurodegenerative disorders in older adults living with HIV, illustrated through a case report where neurologic co-diagnosis of Alzheimer's disease (AD) and HIV-associated Neurocognitive Disorder (HAND) are considered. The patient was followed and evaluated for over 4 years and underwent post-mortem neuropathologic evaluation. Further work is needed to identify diagnostic tests that can adequately distinguish HAND from early stage neurodegenerative disorders among older adults living with HIV and cognitive changes.

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