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TH17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26
- Meller, Stephan;
- Di Domizio, Jeremy;
- Voo, Kui S;
- Friedrich, Heike C;
- Chamilos, Georgios;
- Ganguly, Dipyaman;
- Conrad, Curdin;
- Gregorio, Josh;
- Le Roy, Didier;
- Roger, Thierry;
- Ladbury, John E;
- Homey, Bernhard;
- Watowich, Stanley;
- Modlin, Robert L;
- Kontoyiannis, Dimitrios P;
- Liu, Yong-Jun;
- Arold, Stefan T;
- Gilliet, Michel
Published Web Location
http://www.ncbi.nlm.nih.gov/pubmed/26168081No data is associated with this publication.
Abstract
TH17 cells have important roles at mucosal surfaces in both health and disease. Gilliet and colleagues show that IL-26 is preferentially produced by human TH17 cells and that this cytokine has both alarmin and direct antimicrobial functions.
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