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Regulation of Ras exchange factors and cellular localization of Ras activation by lipid messengers in T cells

  • Author(s): Roose, Jeroen
  • Jun, JE
  • Rubio, I
  • Roose, JP
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3762125?pdf=render
No data is associated with this publication.
Abstract

The Ras-MAPK signaling pathway is highly conserved throughout evolution and is activated downstream of a wide range of receptor stimuli. Ras guanine nucleotide exchange factors (RasGEFs) catalyze GTP loading of Ras and play a pivotal role in regulating rec

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