MicroRNA-based discovery of barriers to dedifferentiation of fibroblasts to pluripotent stem cells.
- Author(s): Blelloch, Robert;
- Judson, RL;
- Greve, TS;
- Parchem, RJ
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3955211?pdf=render
Individual microRNAs (miRNAs) can target hundreds of mRNAs forming networks of presumably cooperating genes. To test this presumption, we functionally screened miRNAs and their targets in the context of dedifferentiation of mouse fibroblasts to induced plu