UCLA Radiological Sciences Proceedings

Langerhans cell histiocytosis (LCH) is a rare myeloid neoplastic disorder typically seen in children and characterized by infiltrative bone lesions. The skin, the lungs, the liver, and the central nervous system may also be involved. Langerhans cell histiocytosis is even more unusual in adults and presents a diagnostic challenge, given that its imaging characteristics are similar to those of other, more prevalent neoplastic processes. We report a case of LCH in a 28-year-old man with neurologic symptoms due to a nonspecific suprasellar mass and a single lytic lesion in the right bony pelvis. The results of histologic evaluation of the lytic lesion confirmed the diagnosis of LCH.