Normal CFTR Inhibits Epidermal Growth Factor Receptor-Dependent Pro-Inflammatory Chemokine Production in Human Airway Epithelial Cells
- Author(s): Nadel, Jay
- Kim, S
- Beyer, BA
- Lewis, C
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3745379?pdf=render
Mutations in cystic fibrosis transmembrane conductance regulator (CFTR) protein cause cystic fibrosis, a disease characterized by exaggerated airway epithelial production of the neutrophil chemokine interleukin (IL)-8, which results in exuberant neutrophil