Skip to main content
eScholarship
Open Access Publications from the University of California

Pocket-sized ultrasonic nebulizer for inhalation drug delivery

  • Author(s): Tsai, CS
  • Mao, RW
  • Lin, SK
  • Zhu, Y
  • Tsai, SC
  • Brenner, M
  • Mahon, S
  • Mukai, D
  • Boss, G
  • et al.
Abstract

Silicon-based MHz ultrasonic multiple Fourier horns in resonance are capable of producing high-throughput micrometer-sized droplets at low drive power. The centimeter-sized nozzles together with low power requirement enabled most recent realization of the first pocket-sized ultrasonic nebulizer (8.6 × 5.6 × 1.5 cm3) that contains nozzle, IC electronic driver, cell-phone battery, micro pump, drug reservoir, and liquid feed. A variety of common drugs for asthma, chronic obstructive pulmonary disease (COPD), diabetics, cyanide poisoning, pulmonary fibrosis, etc. such as albuterol, Humulin U-100, cobinamide, interferon-γ, and budesonide suspension have been nebulized with desirable aerosol size and throughput. © 2013 IEEE.

Many UC-authored scholarly publications are freely available on this site because of the UC Academic Senate's Open Access Policy. Let us know how this access is important for you.

Main Content
Current View