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EvanPhos: a ligand for ppm level Pd-catalyzed Suzuki-Miyaura couplings in either organic solvent or water

  • Author(s): Landstrom, Evan B
  • Handa, Sachin
  • Aue, Donald H
  • Gallou, Fabrice
  • Lipshutz, Bruce H
  • et al.

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A new biaryl phosphine-containing platform can be constructed in only two steps and this complexes Pd(OAc)2 forming a precursor of a very active catalyst useful for Suzuki–Miyaura cross-couplings of functionalized substrates.

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