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Open Access Publications from the University of California

Cranial irradiation alters dendritic spine density and morphology in the hippocampus

  • Author(s): Rosi, Susanna
  • Chakraborti, A
  • Allen, A
  • Allen, B
  • Fike, JR
  • et al.

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Therapeutic irradiation of the brain is a common treatment modality for brain tumors, but can lead to impairment of cognitive function. Dendritic spines are sites of excitatory synaptic transmission and changes in spine structure and number are thought to

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