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Chemoenzymatic synthesis of oligohyaluronan-lipid conjugates

  • Author(s): Szoka, Francis
  • Ruhela, D
  • KivimaÌ̂e, S
  • Szoka, FC
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3993934?pdf=render
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Abstract

Herein, we describe an efficient and high-yielding method to synthesize hyaluronan oligosaccharide-lipid conjugates. This strategy is based on first covalently attaching diphytanoyl glycerophosphatidylethanolamine (DiPhPE) to commercially available high mo

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