UC Berkeley

Metallacyclobutanes are an important class of organometallic intermediates, due to their role in olefin metathesis. They can have either planar or puckered rings associated with characteristic chemical and physical properties. Metathesis active metallacyclobutanes have short M-C_α/α' and M···C_β distances, long C_α/α'-C_β bond length, and isotropic ¹³C chemical shifts for both early d⁰ and late d⁴ transition metal compounds for the α- and β-carbons appearing at ca. 100 and 0 ppm, respectively. Metallacyclobutanes that do not show metathesis activity have ¹³C chemical shifts of the α- and β-carbons at typically 40 and 30 ppm, respectively, for d⁰ systems, with upfield shifts to ca. -30 ppm for the α-carbon of metallacycles with higher d ⁿ electron counts (n = 2 and 6). Measurements of the chemical shift tensor by solid-state NMR combined with an orbital (natural chemical shift, NCS) analysis of its principal components (δ₁₁ ≥ δ₂₂ ≥ δ₃₃) with two-component calculations show that the specific chemical shift of metathesis active metallacyclobutanes originates from a low-lying empty orbital lying in the plane of the metallacyclobutane with local π*(M-C_α/α') character. Thus, in the metathesis active metallacyclobutanes, the α-carbons retain some residual alkylidene character, while their β-carbon is shielded, especially in the direction perpendicular to the ring. Overall, the chemical shift tensors directly provide information on the predictive value about the ability of metallacyclobutanes to be olefin metathesis intermediates.