Single-Stranded Annealing Induced by Re-Initiation of Replication Origins Provides a Novel and Efficient Mechanism for Generating Copy Number Expansion via Non-Allelic Homologous Recombination
- Author(s): Li, Joachim
- Finn, KJ
- Li, JJ
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3536649?pdf=render
Copy number expansions such as amplifications and duplications contribute to human phenotypic variation, promote molecular diversification during evolution, and drive the initiation and/or progression of various cancers. The mechanisms underlying these cop
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