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Analyses of Viral Genetic Networks in the Presence of Missing Data
Abstract
Molecular epidemiology is increasingly used to investigate patterns of HIV transmission. To do so, many analyses consider investigating properties of a sexual or transmission network. The use of sampled data to estimate such properties is a common practice; however, in the presence of missing data, even missing completely at random, networks based on sampled data do not represent their population counterparts. As a result, inferences on sampled networks become unreliable. To address this challenge, we propose statistical approaches to accommodating missing data in the analysis of sampled networks.
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