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What Is the “Relevant” Amyloid β42 Concentration?
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https://doi.org/10.1002/cbic.201900097Abstract
Alzheimer's amyloid beta can perform a wide variety of actions that are highly concentration dependent. This viewpoint aims to provide a framework for basic considerations on what might be considered brain-relevant concentrations of the peptide. Some implications for the therapeutic implementation of the recently emerged oligomer-to-fibril strategy are discussed.
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