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Serological Misdiagnosis of Acute Liver Failure Associated with Echovirus 25 Due to Immunological Similarities to Hepatitis A Virus and Prozone Effect

Abstract

We describe a case of acute liver failure caused by echovirus 25 (E25) in a previously healthy 2-year-old boy. Initial serological studies were consistent with hepatitis A virus (HAV), with prozone phenomenon. The similarity of E25 to HAV may obscure accurate diagnosis in some cases of hepatitis.

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