Autism and Cancer Share Risk Genes, Pathways, and Drug Targets
- Author(s): Crawley, JN
- Heyer, WD
- LaSalle, JM
- et al.
Published Web Locationhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769654/
© 2016 Elsevier Ltd. Autism is a neurodevelopmental disorder, diagnosed behaviorally by social and communication deficits, repetitive behaviors, and restricted interests. Recent genome-wide exome sequencing has revealed extensive overlap in risk genes for autism and for cancer. Understanding the genetic commonalities of autism(s) and cancer(s), with a focus on mechanistic pathways, could lead to repurposed therapeutics.
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