Skip to main content
eScholarship
Open Access Publications from the University of California

UCLA

UCLA Previously Published Works bannerUCLA

Effective use of pre-exposure prophylaxis (PrEP) Among stimulant users with multiple condomless sex partners: a longitudinal study of men who have sex with men in Los Angeles.

  • Author(s): Goodman-Meza, David
  • Beymer, Matthew R
  • Kofron, Ryan M
  • Amico, K Rivet
  • Psaros, Christina
  • Bushman, Lane R
  • Anderson, Peter L
  • Bolan, Robert
  • Jordan, Wilbert C
  • Rooney, James F
  • Wohl, Amy R
  • Landovitz, Raphael J
  • et al.

Published Web Location

https://pubmed.ncbi.nlm.nih.gov/30894013/
No data is associated with this publication.
Abstract

PrEP's potential benefit for men who have sex with men (MSM) who use stimulants may be limited by adherence or prescriber willingness to recommend PrEP due to concerns of non-compliance. Using data from PATH-PrEP, a 48-week study evaluating PrEP for MSM in Los Angeles, we modeled an interaction between stimulant use and condomless sex with multiple partners (CAS-MP) on prevention-effective dried blood spot tenofovir-diphosphate concentrations. At week 4, participants reporting stimulant use and CAS-MP had a decreased odds of prevention-effective adherence compared to non-stimulant use and non-CAS-MP (AOR 0.15, 95% CI 0.04-0.57). From week 4-48, participants reporting stimulant use and CAS-MP had increased odds of prevention-effective adherence (AOR 1.06 per week, 95%CI 1.01-1.12). Participants reporting CAS-MP without stimulant use had no significant change in prevention-effective adherence (AOR 0.99 per week, 95%CI 0.96-1.02). Stimulant use moderated the association of CAS-MP on prevention-effective PrEP adherence over time.

Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.

Main Content

This item is under embargo until June 17, 2021.

You may have access to the publisher's version here:

https://pubmed.ncbi.nlm.nih.gov/30894013/Notify me by email when this item becomes available