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Unraveling the mechanism of cell death induced by chemical fibrils

  • Author(s): Wells, James
  • Weissman, Jonathan
  • Kampmann, Martin
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4201873?pdf=render
No data is associated with this publication.
Abstract

© 2014 Nature America, Inc. All rights reserved.We previously discovered a small-molecule inducer of cell death, named 1541, that noncovalently self-assembles into chemical fibrils ('chemi-fibrils') and activates procaspase-3 in vitro. We report here that

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