Targeting and transport: How microtubules control focal adhesion dynamics
- Author(s): Wittmann, Torsten
- Stehbens, S
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3514042?pdf=render
Directional cell migration requires force generation that relies on the coordinated remodeling of interactions with the extracellular matrix (ECM), which is mediated by integrin-based focal adhesions (FAs). Normal FA turn-over requires dynamic microtubules