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Targeting and transport: How microtubules control focal adhesion dynamics
Published Web Location
http://europepmc.org/articles/PMC3514042?pdf=renderNo data is associated with this publication.
Abstract
Directional cell migration requires force generation that relies on the coordinated remodeling of interactions with the extracellular matrix (ECM), which is mediated by integrin-based focal adhesions (FAs). Normal FA turn-over requires dynamic microtubules
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